When I asked Eduard how he
likes working at Genentech, he told me that he loves working and being here,
with a big smile on his face. He was sincerely bound to his workplace. What
makes this story special is that Edison was not one of the highest-paid
employees at the top management level, in contrast, he was probably at the bottom
scale in the company, cleaning dirty cages of the animals.
When my interest in
working in the US was combined with my curiosity to learn more about how the
brain functions in health and disease, I contacted Dr. Morgan Sheng at MIT.
During our phone interview, he told me that he was moving to Genentech soon, if
I was to come to his lab, I could join him at Genentech. I must admit that I
did not know much about Genentech before that phone conversation. He briefly
mentioned that it is a great place, and I should just check it out. I
immediately googled Genentech and started reading about it on the Wikipedia
page…Besides numerous achievements in research, Genentech was number 1 employer
in Forbes Magazine “100 places to work in the US” in 2006 and 2nd after Google
in 2007. Neither in Turkey or Germany, I was aware of the ‘best places to work
for’ concept. As science scholars, we normally don’t really think about how we
are treated at work anyway. While being at the top of the list sounded only good,
it did not have much impact on me, first, because I was not really aware of
what it means, and second, I cared more about resources as a scientist that
would be given to me to do great research.
As soon as I signed the
contract with Genentech, I started receiving calls/emails from various people
regarding my needs to live in the US: my visa, driver’s license, bank account,
finding an apartment etc. Various professional services hired by the company
were responsible for the relocation of new employees, and they take literally
care of everything. When I arrived in the US, I was given a rental car and
hotel. The next day Kelly from the relocation company picked me up and showed me
neighborhoods in San Francisco and explained why they are good or not. Then
when I told her that I liked the Pacific Heights neighborhood, she made
appointments on the same evening and picked me up the next day to visit the
apartments. With her help, I could find a great place on the same day. San
Francisco has probably one of the toughest rental markets in the world but with
such professional help, it went smoothly. An additional problem for me as
someone just moving to the US was not having a credit history (meaning that a
person needs to have various transactions with banks/credit cards over
months/years to prove that they are financially trustable). This makes it
difficult for foreigners to rent a place with regular market prices. After
hearing that I just started working at Genentech, the landlady did not
request my non-exciting credit history and rented me our lovely place at the
most beautiful part of the city:). All these sequels of events, even before I
stepped into the company, did prove the care that they give to employees and
further showed me the existence of a high quality work environment.
There are probably many
details and stories how Genentech –and similarly successful companies in the
US– treats employees at different levels. I would like to give examples of my
experiences and my friends at Genentech are of course welcome to add their
experiences and thoughts in the comment section.
First of all, what I
really like about Genentech was the quality of the food. I love food, as all
of you do I am sure. and I have never been to a work environment that has
better food quality. In various cafeterias at Genentech, there is a variety of
cuisines including Japanese, Mexican, Italian, Asian, etc. I particularly loved
Rotisserie, Sushi, and Pasta. My pasta chef was from Spain and we always had
chats about football, life in America compared to Europe, and so forth while he
prepared my special whole-wheat fettuccini with fresh seafood (muscles,
salmon, tuna, shrimps or even sometimes with halibut and scallops), which were
not on the regular menu. That was special to me. Overall, I loved the
options of having whole wheat bread, pasta, even brown rice for the sushi. In
addition, the food at Genentech is relatively cheap and very high quality as
being organic, fresh, and also with many local selections.
The quality of food with
tons of healthy selections is not the only way to keep people healthy and fit.
Genentech has a great gym within the campus, with a SPA and all kinds of machines
and courses. In addition, we could use a larger gym close by for free, which
has a swimming pool and tennis courts. I visited the gym about 4-5 times per
week. In addition to keeping myself fit and relaxing in my mind, I loved chatting
with people from different divisions, which otherwise I would have probably
never met in a company with 12000 employees. I also played at the Genentech
soccer team. We went to RIFT (Roche International Football Tournament), which
took place in different countries in Europe every year, for which the company
paid all costs of the team.
Some additional amazing
services that I benefited are in a campus car wash, dry clean, medical unit, and
concierge. For example, I could leave the car more or less where I park every day, and they would wash it while I work. If you want to book a table at
French Laundry –which was chosen as the best restaurant in the world 2 times in a
row– you call the concierge, they will do it for you. Otherwise, one has to try
calling several days until finding a table –probably some time earliest 2-3
months later.
Genentech is also a green
company that cares and courageous employees to care for the environment. Already
many electric vehicles are used on campus. There are also several shuttles
(with Wi-Fi) from the city to work and back (even though I preferred to drive:)) to
reduce the individual driving, and on-campus bikes that everyone can use.
Fascinatingly, the company pays you additionally every time you take the
shuttle, bike to work, or carpool.
The company would also
make regular happy hours (parties) with food and music, and organize large
events during special days like Halloween or Christmas with entertainment,
music, delicious food for thousands of employees and their families. Once a
year, there is a Giveback event that goes for a week. During this week, the
company and the employees make donations, and involve in charitable activities,
for example, going to neighborhoods in the city and helping people to build
their houses, schools, etc., which fills up our contentment tank. After all, we
become most happy when we give to others (sounds like another article topic
here:)). “Do you have any idea who is coming”…”I heard that Lady Gaga is in
town” are regular talks every year to guess who will take the stage at
Genentech’s annual AT&T park concert, where famous artists/bands like Black
Eye Peas, Pitbull, and Bruno Mars appeared. In addition, during the concert, all
food and drinks are free as much as you can eat:). Everyone is allowed to bring
one additional person and their kids, which at the end probably becomes
something like 20-25 thousand people. Imagine the cost of such an event, which
is organized solely to make the employee and their family happy.
There are regular surveys
to evaluate the company, where employees can give their feedback regarding the
company’s policies and culture. Indeed, Fortune Magazine’s "100 Best
Companies To Work For" is based on such anonymous employee responses to
the survey. There is also a regular evaluation of the individual employee from
the people they work with. This helps to identify how the individuals can fit
to the company’s work environment, whether they contribute or not. For example,
if there is a bad manager you and some others suffer from; you have a good
chance to make a change with your feedbacks contrary to most of the other workplaces where one usually does not have any power to criticize upper management.
In academia, it is mostly
individuals who are responsible for themselves and their efficiency, however,
in a company like Genentech, individuals are pieces of a whole unit and need
to learn how to communicate and work together with others to make great
discoveries that could change the world. I really enjoyed learning this aspect
of work ethics. I believe that I improved over the years from being a rather
individual researcher, to someone who could see and value collective team
efforts. The more I learned about Genentech and the Bay Area culture, the easier
it got for me to communicate with others and follow some regulations –which
were originally against my rebellious personality :)- that are needed for the
protection of the entire system.
Because of such great
benefits and work environment, Genentech can hire the best scientists and
conduct the most cutting-edge research. Hence, Genentech has become a top-notch biotech firm with world-renowned researchers. It has a great postdoctoral
program (where I worked) that aims to generate excellent basic research and
publications like a university. Many people asked me why Genentech invests so
much in basic research, where the money is spent on not producing drugs but rather
to explore basic principles of science. I believe there are two main
motivations behind this: first, Genentech can hire great scientists from
academic environments by saying, look, you can come to us and still continue
doing basic research that you love, while you can contribute to finding
treatments for devastating diseases to make a substantial impact. Secondly,
Genentech still can benefit from basic research in the long-term for drug
development even though it may cost more effort and money. For example, one of
the most famous drugs of the company for a breast cancer treatment called
Herceptin was the result of a postdoctoral fellow exploring the basic biology
behind the HER2 gene. Almost every basic research topic even if they look so
far from it has a therapeutical value. The capacity to translate such
knowledge into a treatment that the human being can benefit needs time, large
investments, and cooperation of many divisions to develop the idea. Genentech
has these valuable assets.
Besides all the good
aspects, naturally, there is always room to grow and get better. Sometimes
people in such great companies may think that there is already a lot of
achievements accomplished and not much to learn and improve. Therefore, they
might be more closed to feedbacks and critics. Expression of our thoughts to
people with a predetermined mind needs extra skills in communication. Overall,
I learned that being “politically correct” is a safer and more effective way to
express my opinions rather than directly putting a finger on the issue, which
is not very welcomed in the American culture. I am not going into details of
this topic but I can recommend a few books, which can help to improve your
communication skills and be more effective when the stakes are high: “Crucial
Conversations” by Kerry Patterson and “The 7 Habits of Highly Effective People:
Powerful Lessons in Personal Change” by Stephen R. Covey. Finally, there will
be always some people who are not happy with the company regardless of the quality
and improvements even if well majority of the employee is very content. This
could be simply due to incompatibility between these individuals and the work
ethics/environment of the company. In such cases, one may need to take more
concrete steps and move on to a better fitting environment instead of
accumulating negative feelings/thoughts over time.
Finally, I would like to
talk a bit about research at Genentech in simple words. Genentech is famous
for its antibody-based drugs for cancer treatments. A typical Pharmaceutical
company, which aims to develop drugs, makes screens with thousands maybe
millions of chemicals. For example, if they want to find out a drug that kills
the cancer cells, the different chemicals are dropped onto isolated cancer cell
lines in laboratory conditions to find out which chemical can kill the cancer
cells. The main advantage of this approach is that it is fast and cost
effective. The downside of this approach is that it is very hard to know what
other effects would these chemicals have when they are given to humans. For
example, the chemicals that can kill the cancer cells may also kill healthy
cells in the body. In a metaphor, this can be considered as a zombie hunter in a
large city. Let’s assume that we want to develop a drop of toxin that can
eliminate some zombies hidden in the city before they expand more and further
harm the city and people. If we were to mix our potential toxin medicine into
raindrops, this toxin would affect almost every individual in the city, and
besides zombies, many people would also die. Because of the same reason, people
who receive chemotherapy for cancer treatment may lose their hair and
partially destroy various other tissues, hence they have serious side effects.
As the first biotech company in the world, Genentech started with a different
approach to develop drugs and bring treatment to people. The mission had been,
first, to understand the biology behind the disease and later target the cancer
cells or pathogens more specifically by employing biological substances. This
is also the base of personalized medicine, which you probably started to
hear more and more. For example, in cancer studies, Genentech tries to discover
specific features of cancer cells and subsequently targets them with antibodies
that can kill only cancer cells. This can be considered as guided-toxins in the
zombie hunt. The aim is to release the toxins only when a real zombie (real
zombie? :)) is on target. To this end, of course, one has to figure out
unmistakably what a zombie is and what not and how to deliver the toxin
specifically to an individual zombie. While typical chemotherapy is designed
to kill anyone, for example, it is delivered as raindrops and would kill anyone
walking regardless being a human or zombie, an antibody can be more targeted,
for example, it can be carried by trained soldiers and delivered onto creatures
that walk with an awkward shamble posture unlike a typical human who stands
straight (for more info read Physical Characteristics of Zombies). Therefore, only when we could find out what
makes cancer cells (zombies) different from normal healthy cells (human being),
then we could specifically find and eliminate the bad guys to protect the
healthy ones.
Overall, I had a great
experience at Genentech and strongly suggest it to anyone who would like to
work in such an environment (there were no zombies :)). Apart from the basic neuroscience projects that I
performed aiming to understand how our brain functions, I also learned a great
deal about translational research, that aims to discover new drugs and
treatments for devastating diseases. In the next article, I would like to talk
more about my research more in detail. I know that there is a clear
communication problem between scientists and the rest of society, which
is mostly due to the complicated nature of science and our inability to
simplify it correctly for non-scientist. I am down to give it a try :), which
might be helpful for many people around me finally to understand what actually
I am doing.
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